Quality management in the medical and pharmaceutical industry (GMP)

The course explains the quality management requirements for production processes in specific areas. The first part of the course deals with "Good Manufacturing Practice" (GMP), which describes the guidelines for quality assurance of production processes and environments, for example in the pharmaceutical industry, but also in the production of cosmetics, food and animal feed. The second part deals with quality management specifically for the manufacture of medical devices. Based on the Medical Device Regulation (MDR), every company manufacturing in this area must set up, document and manage a risk management system to ensure the safety of its products. In addition, an insight is given into the use of artificial intelligence for this professional field.
  • Certificates: GMP - Good Manufacturing Practice" certificate
    Certificate "Quality management in the medical device industry"
  • Examination: Praxisbezogene Projektarbeiten mit Abschlusspräsentationen
  • Teaching Times: Full-time
    Monday to Friday from 8:30 a.m. to 3:35 p.m. (in weeks with public holidays from 8:30 a.m. to 5:10 p.m.)
  • Language of Instruction: German
  • Duration: 8 Weeks

GMP - Good Manufacturing Practice

Introduction to GMP (approx. 2 days)

EU GMP guidelines, AMG, AMWHV

Authorities, drug approvals, marketing authorization

Key persons

FDA, CFR 21

International regulations

AI in the pharmaceutical environment


SOP system (approx. 2.5 days)

Requirements for SOPs

Structure of SOPs

Document control and version management


Training system (approx. 1.5 days)

Employee qualification

Training planning and documentation

Effectiveness control


Deviation and CAPA management (approx. 2 days)

Deviations and CAPA

Requirements for deviation and CAPA management

Documentation of deviations

Error cause analysis

Corrective and preventive measures

CAPA process

AI-supported data analysis for root cause identification


Change management (change control) (approx. 1 day)

Requirements for change management

Notifiable changes, classification of changes

Risk management in the change process

Change management process


Validation and qualification (approx. 1.5 days)

Device, system and room qualification

Process, cleaning and method validation

Qualification and validation process

Qualification and validation documentation


Quality control (approx. 1 day)

Sampling and testing

stability

Dealing with OOS

Storage status

AI-supported evaluation of test data


Complaints management (approx. 0.5 days)

Complaints

Product recall


Audit management (approx. 0.5 days)

Audit types and audit process

Internal audit and FDA inspection

AI-supported data analysis for audit preparation


Supplier qualification (approx. 0.5 days)

Supplier qualification and evaluation


Review and trending (approx. 0.5 days)

Batch Record Review

Product Quality Review

Management Review


Industrial hygiene in the pharmaceutical industry (approx. 2 days)

Personnel hygiene

Hygiene requirements

Clothing and behavior

Production hygiene

Contamination prevention

Hygiene plans


Documentation (approx. 0.5 days)

GMP documentation and data integrity

AI-supported support for document review


Production rooms - clean rooms (approx. 1 day)

General requirements for production rooms

Requirements for premises including storage areas

Avoidance of cross-contamination


Project work (approx. 3 days)

To consolidate the content learned

Presentation of the project results

QM in the medical device industry

Introduction to general quality management (approx. 1 day)

Basics of QM

Q-methods and Q-tools


QM - Medical devices ISO 13485 (approx. 2 days)

Structure, scope, area of application of ISO 13485

Relationship between MDR/IVDR and ISO 13485

ISO 13485 in the context of the requirements of 21 CFR Part 820


Requirements for management systems (approx. 3 days)

Management standard ISO 9001:2015

Provision and management of resources

Basics in the area of measurements and tests

Requirements for measuring equipment management for medical devices/diagnostics


Artificial intelligence (AI) in the work process

Presentation of specific AI technologies

and possible applications in the professional environment


Process-oriented QM (approx. 4 days)

Meaning of process, process orientation, process description and process validation

Corrective and Preventive Actions (CAPA process)

Continuous improvement process (CIP)

Monitoring products on the market: defect and complaint management, postmarket surveillance (PMS and PMCF), reporting procedures and complaint handling

Communication with the authorities and notified bodies: Feedback and reporting


Documentation systems (approx. 3 days)

Basics of general QM documentation, document control and archiving

Validation parameters (IQ, OQ, PQ)

Summary Technical Documentation: STED


Risk management (approx. 2 days)

Importance of the risk management standard ISO 14971

Product and process risks

Risk areas, typical product risks


Audits and inspections (approx. 2 days)

Application of EN ISO 13485

Certifiers or the responsible authorities

EN ISO 13485 vs. MDR (Medical Device Regulation)

ISO 13485 as the basis for the global MDSAP (Medical Device Single Audit Program)

Auditor duties, audit planning and implementation

Audits taking into account the implementation of legal and technical requirements


Project work (approx. 3 days)

To consolidate the content learned

Presentation of the project results



Changes are possible. The course content is updated regularly.

After this course, you will be familiar with the requirements of a GMP system, the applicable regulations and the central processes of pharmaceutical quality management. You will understand the basics of SOP systems, CAPA, change management, audit processes, documentation, quality control, industrial hygiene and cleanroom requirements and be able to classify relevant technical terms with confidence.

You are also familiar with the regulations, standards and certifications for medical devices and can contribute to the implementation of EN ISO 13485:2021-12.

The course is aimed at science students, engineering graduates, production managers, quality officers and all employees in pharmaceutical production, technology, quality control and quality assurance. It is also aimed at all persons who are responsible for compliance with "Good Manufacturing Practice" and want to find out about the core GMP topics.

GMP knowledge is indispensable in almost all areas of the production of pharmaceuticals and active ingredients, as well as cosmetics, food and animal feed. Your newly acquired knowledge will open up numerous new opportunities for you in these sectors.

Your meaningful certificate provides a detailed insight into the qualifications you have acquired and improves your career prospects.

Didactic concept

Your lecturers are highly qualified both professionally and didactically and will teach you from the first to the last day (no self-study system).

You will learn in effective small groups. The courses usually consist of 6 to 25 participants. The general lessons are supplemented by numerous practical exercises in all course modules. The practice phase is an important part of the course, as it is during this time that you process what you have just learned and gain confidence and routine in its application. The final section of the course involves a project, a case study or a final exam.

 

Virtual classroom alfaview®

Lessons take place using modern alfaview® video technology - either from the comfort of your own home or at our premises at Bildungszentrum. The entire course can see each other face-to-face via alfaview®, communicate with each other in lip-sync voice quality and work on joint projects. Of course, you can also see and talk to your connected trainers live at any time and you will be taught by your lecturers in real time for the entire duration of the course. The lessons are not e-learning, but real live face-to-face lessons via video technology.

 

The courses at alfatraining are funded by Agentur für Arbeit and are certified in accordance with the AZAV approval regulation. When submitting a Bildungsgutscheinor Aktivierungs- und Vermittlungsgutschein, the entire course costs are usually covered by your funding body.
Funding is also possible via Europäischen Sozialfonds (ESF), Deutsche Rentenversicherung (DRV) or regional funding programs. As a regular soldier, you have the option of attending further training courses via Berufsförderungsdienst (BFD). Companies can also have their employees qualified via funding from Agentur für Arbeit (Qualifizierungschancengesetz).

We will gladly advise you free of charge.

0800 3456-500 Mon. - Fri. from 8 am to 5 pm
free of charge from all German networks.

Contact

We will gladly advise you free of charge. 0800 3456-500 Mon. - Fri. from 8 am to 5 pm free of charge from all German networks.