GMP and GCP

With "Good Manufacturing Practice" (GMP) and "Good Clinical Practice" (GCP), the course combines two essential topics of quality management. The first part of the course describes the guidelines for quality assurance of production processes and environments, for example in the pharmaceutical industry, but also in the cosmetics, food and animal feed industries. The second part of the course uses the ICH-GCP quality standard to present regulatory knowledge and practical know-how for conducting clinical trials that are set up according to ethical and scientific criteria. An introduction to the use of artificial intelligence in these areas rounds off the course.
  • Certificates: GMP - Good Manufacturing Practice" certificate
    GCP - Good Clinical Practice" certificate
  • Examination: Praxisbezogene Projektarbeiten mit Abschlusspräsentationen
  • Teaching Times: Full-time
    Monday to Friday from 8:30 a.m. to 3:35 p.m. (in weeks with public holidays from 8:30 a.m. to 5:10 p.m.)
  • Language of Instruction: German
  • Duration: 8 Weeks

GMP - Good Manufacturing Practice

Introduction to GMP (approx. 2 days)

EU GMP guidelines, AMG, AMWHV

Authorities, drug approvals, marketing authorization

Key persons

FDA, CFR 21

International regulations

AI in the pharmaceutical environment


SOP system (approx. 2.5 days)

Requirements for SOPs

Structure of SOPs

Document control and version management


Training system (approx. 1.5 days)

Employee qualification

Training planning and documentation

Effectiveness control


Deviation and CAPA management (approx. 2 days)

Deviations and CAPA

Requirements for deviation and CAPA management

Documentation of deviations

Error cause analysis

Corrective and preventive measures

CAPA process

AI-supported data analysis for root cause identification


Change management (change control) (approx. 1 day)

Requirements for change management

Notifiable changes, classification of changes

Risk management in the change process

Change management process


Validation and qualification (approx. 1.5 days)

Device, system and room qualification

Process, cleaning and method validation

Qualification and validation process

Qualification and validation documentation


Quality control (approx. 1 day)

Sampling and testing

stability

Dealing with OOS

Storage status

AI-supported evaluation of test data


Complaints management (approx. 0.5 days)

Complaints

Product recall


Audit management (approx. 0.5 days)

Audit types and audit process

Internal audit and FDA inspection

AI-supported data analysis for audit preparation


Supplier qualification (approx. 0.5 days)

Supplier qualification and evaluation


Review and trending (approx. 0.5 days)

Batch Record Review

Product Quality Review

Management Review


Industrial hygiene in the pharmaceutical industry (approx. 2 days)

Personnel hygiene

Hygiene requirements

Clothing and behavior

Production hygiene

Contamination prevention

Hygiene plans


Documentation (approx. 0.5 days)

GMP documentation and data integrity

AI-supported support for document review


Production rooms - clean rooms (approx. 1 day)

General requirements for production rooms

Requirements for premises including storage areas

Avoidance of cross-contamination


Project work (approx. 3 days)

To consolidate the content learned

Presentation of the project results

GCP - Good Clinical Practice

Introduction and definitions (approx. 2 days)

Medical basics and terminology

Legal, regulatory and ethical framework conditions

Planning and organization of studies

Forms of studies, study methodology

Application to an ethics committee


GCP definitions/important GCP documents (approx. 3 days)

Legal basis and regulations in clinical research

National and international principles of pharmaceutical law/ICH-GCP

Declaration of Helsinki

ICH-GCP E6 (R3) regulations


Artificial intelligence (AI) in the work process

Presentation of specific AI technologies

and possible applications in the professional environment


Introduction to clinical trials (approx. 4 days)

Resource planning

Distribution of tasks in the team

Investigator contract

Relevant documents: protocol, investigator's brochure, information, CRF, etc.

Responsibilities (sponsor, CRO, monitor, investigator)


Introduction to the processes of clinical data management (approx. 3 days)

Electronic recording, plausibility check and coding of study data


Medical statistics and biometrics (approx. 1 day)

Basic statistical concepts

Data management

Database management


Audits/inspections (approx. 2 days)

Informing study participants; §40 and 41 AMG

Documentation and reporting of adverse events

Adverse events: Definitions, reporting channels, reporting deadlines

Quality management of clinical trials


Completion of the clinical trial (approx. 2 days)

Close Out Visit

Archiving and final study reports


Project work (approx. 3 days)

To consolidate the content learned

Presentation of the project results



Changes are possible. The course content is updated regularly.

After this course, you will be familiar with the requirements of a GMP system, the applicable regulations and the central processes of pharmaceutical quality management. You will understand the basics of SOP systems, CAPA, change management, audit processes, documentation, quality control, industrial hygiene and cleanroom requirements and be able to classify relevant technical terms with confidence.

You will also master the legal, ethical and administrative aspects of GCP as well as the specialist knowledge of clinical trials from planning to statistical evaluation.

The course is aimed at science students, engineering graduates, production managers, quality officers and all employees in pharmaceutical production, technology, quality control and quality assurance. It is also aimed at all persons who are responsible for compliance with "Good Manufacturing Practice" and want to find out about the core GMP topics.

Professional knowledge and consistent adherence to prescribed standards are required to ensure high quality in clinical trials. With these newly acquired skills, you will be in high demand in the pharmaceutical industry or at a contract research organization.

Additional GMP knowledge is essential in almost all areas of the production of pharmaceuticals and active ingredients, as well as cosmetics, food and animal feed. Your newly acquired knowledge will open up numerous new opportunities for you in these sectors.

Didactic concept

Your lecturers are highly qualified both professionally and didactically and will teach you from the first to the last day (no self-study system).

You will learn in effective small groups. The courses usually consist of 6 to 25 participants. The general lessons are supplemented by numerous practical exercises in all course modules. The practice phase is an important part of the course, as it is during this time that you process what you have just learned and gain confidence and routine in its application. The final section of the course involves a project, a case study or a final exam.

 

Virtual classroom alfaview®

Lessons take place using modern alfaview® video technology - either from the comfort of your own home or at our premises at Bildungszentrum. The entire course can see each other face-to-face via alfaview®, communicate with each other in lip-sync voice quality and work on joint projects. Of course, you can also see and talk to your connected trainers live at any time and you will be taught by your lecturers in real time for the entire duration of the course. The lessons are not e-learning, but real live face-to-face lessons via video technology.

 

The courses at alfatraining are funded by Agentur für Arbeit and are certified in accordance with the AZAV approval regulation. When submitting a Bildungsgutscheinor Aktivierungs- und Vermittlungsgutschein, the entire course costs are usually covered by your funding body.
Funding is also possible via Europäischen Sozialfonds (ESF), Deutsche Rentenversicherung (DRV) or regional funding programs. As a regular soldier, you have the option of attending further training courses via Berufsförderungsdienst (BFD). Companies can also have their employees qualified via funding from Agentur für Arbeit (Qualifizierungschancengesetz).

We will gladly advise you free of charge.

0800 3456-500 Mon. - Fri. from 8 am to 5 pm
free of charge from all German networks.

Contact

We will gladly advise you free of charge. 0800 3456-500 Mon. - Fri. from 8 am to 5 pm free of charge from all German networks.